Phenotypic and functional characteristics of intestinal intraepithelial lymphocytes during acute rejection of small intestinal allografts

Small Intestinal Intraepithelial Lymphocytes Maximum Immunobioactivity of Murine

Cell Density Counts of the Intestinal Intraepithelial Lymphocytes in the Celiac Patients

Background: Increased number of intestinal intraepithelial lymphocytes (IELs) is a key histological finding in the diagnosis of celiac disease (CD); however, the number of IELs in celiac patients and healthy subjects may vary from one region to another. Additionally, there are some seronegative celiac patients with a borderline histology. Objective: To determin...

Potent Protective Cytotoxic Activity During Intestinal Intraepithelial Lymphocytes Exert

Intestinal intraepithelial lymphocytes: the plot thickens

O ver the last few years, the characterization of T lyraphocytes within the intestinal epithelium (ilEL) has revealed phenotypic and functional heterogeneity that rivals only that observed within the thymus. Of note in this context is that thymic and intestinal epithdia share the same embryologic origin in that they are both derived from endoderm. Several lines of evidence have led to the concl...

Phenotypic and functional characterization of intraepithelial lymphocytes in a bovine ligated intestinal loop model of enterohaemorrhagic Escherichia coli infection.

Ruminants are a major reservoir of enterohaemorrhagic Escherichia coli (EHEC), which cause acute gastroenteritis in humans with potentially life-threatening sequelae. The mechanisms underlying EHEC persistence in ruminant hosts are poorly understood. EHEC produce several cytotoxins that inhibit the proliferation of bovine lymphocytes in vitro and influence EHEC persistence in calves, suggesting...